That would be awesome, I think that would be about as benign as injection, taking it through mucous membrane bypasses the digestive system, which is generally way more problematic.
Mouselemming@sh.itjust.works
on 15 May 14:17
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And seems to me it ought to be extra effective if the immune reaction is centered near the usual source of the infection. Unless you have a bad reaction to the vaccine of course
Animal studies show it is way more effective. You want to activate and train the immune cells that will first be exposed to the virus. Traditional needle base vaccines help deal with the virus once it’s already in your body. Great for managing the infection and ensuring it’s scope is limited.
A nasal vaccine could stop people from being infected at all. Which is what they saw in animal studies so far.
HubertManne@piefed.social
on 15 May 17:07
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I mean individual wise I think you just don’t get it and maybe mental health in general. TLDR - just get over it or go find some therapy and bingo bango boom. done. Society wise having resources would at least make it more possible for people who try. Honestly though its likely cheaper and easier to just have a nasal spray option but its holistically better for the individual to just not have phobias or really any mental health problems.
homura1650@lemmy.world
on 15 May 15:19
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We’ve had nasal flu vaccines for decades.
tobebannedbygaymods@lemmy.zip
on 15 May 17:25
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I got like 9 or 11 injections in one 30-sec army jabfest in 91. I still don’t like needles, but I’ll roll up my arm or drop trou for something beneficial with no complaint. The alternative is always worse.
There will be outbreaks of other corona viruses in the future. I wonder if this medicine will be effective against them or at least will be a baseline from which adjustments can be more quickly made to be effective against a different corona virus. This is one of the most positive news stories I’ve seen today.
HubertManne@piefed.social
on 15 May 16:37
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Ensitrelvir works by blocking a key enzyme that the virus relies on to make new copies of itself. This enzyme is also targeted by Paxlovid. But unlike Paxlovid, ensitrelvir was shown to significantly reduce the risk of developing COVID-19 symptoms compared to a placebo among those who had been exposed to the virus.
tobebannedbygaymods@lemmy.zip
on 15 May 17:26
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No, this doesn’t prime your immune system; it works directly against the virus, so you need the drug in your system actively to benefit from the effects.
threaded - newest
Just give me a nasal vaccine please
That would be awesome, I think that would be about as benign as injection, taking it through mucous membrane bypasses the digestive system, which is generally way more problematic.
And seems to me it ought to be extra effective if the immune reaction is centered near the usual source of the infection. Unless you have a bad reaction to the vaccine of course
Animal studies show it is way more effective. You want to activate and train the immune cells that will first be exposed to the virus. Traditional needle base vaccines help deal with the virus once it’s already in your body. Great for managing the infection and ensuring it’s scope is limited.
A nasal vaccine could stop people from being infected at all. Which is what they saw in animal studies so far.
Imagine if your annual vaccination was a simple nose spray.
That doesn’t sound much different than a traditional vaccine, unless you can self administer it
its massive for needlephobes.
Probably get more return on resources investing in therapy to address phobias, in that case.
you mean society or the individual?
Both
I mean individual wise I think you just don’t get it and maybe mental health in general. TLDR - just get over it or go find some therapy and bingo bango boom. done. Society wise having resources would at least make it more possible for people who try. Honestly though its likely cheaper and easier to just have a nasal spray option but its holistically better for the individual to just not have phobias or really any mental health problems.
We’ve had nasal flu vaccines for decades.
People take Annual Vaccines ?
There’s been a nasal flu vaccine for a while but it’s not as effective as the intramuscular ones.
Some of us really hate spraying stuff up our noses. I'll keep my injection, thanks.
I got like 9 or 11 injections in one 30-sec army jabfest in 91. I still don’t like needles, but I’ll roll up my arm or drop trou for something beneficial with no complaint. The alternative is always worse.
There will be outbreaks of other corona viruses in the future. I wonder if this medicine will be effective against them or at least will be a baseline from which adjustments can be more quickly made to be effective against a different corona virus. This is one of the most positive news stories I’ve seen today.
Ensitrelvir works by blocking a key enzyme that the virus relies on to make new copies of itself. This enzyme is also targeted by Paxlovid. But unlike Paxlovid, ensitrelvir was shown to significantly reduce the risk of developing COVID-19 symptoms compared to a placebo among those who had been exposed to the virus.
So basically a vaccine ?
No, this doesn’t prime your immune system; it works directly against the virus, so you need the drug in your system actively to benefit from the effects.
…Wait, wouldn’t that literally make it a cure for the common cold?